computational biology 2019
Computational and Structural Biology Conference cordially invite you all to attend the Euroscicon Conference on Computational and Structural Biology during September 11-12, 2019 at Seoul, South korea. This is an amazing opportunity for the participants from different Universities and Institutions to interact with the most proficient Scientists world-wide. Computational and Structural Biology 2019 will be a global stage for sharing information and ability from both scientific and industrial groups. The conference will impact an attractive moment to interact with professionals in the research field and therefore it takes a delight in opening a gate to meet young researchers and potential speakers where they can demonstrate their novel research and contributions in the field of Structural biology and Biochemistry. Computational and Structural Biology 2019 meet your target audiences from around the world focused on learning about Molecular Structures of macromolecules and Structural alterations and This conference would be your single best opportunity to reach the largest assemblage of participants from the Biotechnology and Biochemistry community.
The Computational and Structural Biology 2019 Conference will provide:
- A Global network with 50+ countries.
- A pre-requisite platform Sponsors & exhibitors
- Explicit talks by the eminent scientists of the global scientific community.
- Sterling workshop sessions.
- Global Recognition to meritorious Researchers.
- Novel Techniques benefiting your research.
- Global Business and Networking Opportunities.
Why to attend?
Meet your target market with recent business reports on Structural Biology and drug designing making news which manifests the tremendous growth in market value for pharmaceutical industry. Since Structural biology focuses on Structure determination through X-ray crystallography, NMR, Cryo-EM; computational structure prediction; identification of signaling pathways and drug designing through various bioinformatics software, it would be a great opportunity for companies dealing with analytical instruments and software useful in these conference which will be conducted by experts in the respective fields. Also many upcoming students and Researchers can benefit themselves by participating in world class International workshops, symposia.
- Executives, CEO of Organisation
- Directors/Managers & Business Delegates
- Founders, Director of Laboratories, Universities, Industries
- Investigators and Researchers
- Post-Doctoral Fellows
- Research and Diagnostic Laboratories
- Clinical Fellows
- Research Scholars
- Technology Experts
- Biomedical Research companies.
Rise in the number of clinical trials, toxicological studies, and health awareness for nutritional products, rapid growth of structural biology analytical instruments, software and solutions, and use of structural biology as a base for drug designing will propel the growth of pharmaceuticals market.
What is Computational Biology?
Computational Biology has a wide range of usage in Biotechnology and Pharmaceuticals. Therefore, large Bioinformatics R & D divisions are being established in many pharmaceutical companies, biotechnology companies and even in other conventional industry dealing with biology. This field is thus rated as number one career in the field of Biosciences. It uses advances in the area of computer science, information science, computer and information technology, communication technology to solve complex problems in life. Data capture, data warehousing and data mining have become major issues for Biotechnologists and Biological scientists due to sudden growth in quantitative data in biology such as complete genomes of biological species including human genome, protein sequences, protein 3-D structures, metabolic pathways databases, cell line & hybridoma information, biodiversity related information.
What is Structural Biology?
Structural biology is an interdisciplinary science which is mainly focused on the study of Molecular Structures and Dynamics of Biological macromolecules, the proteins, nucleic acids and how these alterations are occurred in their structures affecting their function. Structural biology incorporates the principles of molecular biology, biochemistry and biophysics regarding the molecular structure of biological macromolecules. It even provides information about the structural alterations and thus affecting their function. This process of determination of structures of proteins, nucleic acids takes years as the shape, size and assemblies of the molecules keep altering the function.
Scope and Importance
Computational and Structural Biology mainly focuses on the emerging and wide-ranging interrelated science which implicates the new techniques in predicting the 3D structures of proteins of unknown structure and in designing the new protein structures using the Computational Techniques and the Computational Biology.
The studies further continues with the increase in understanding of the diversified roles of play of the molecules in biology and to urging the Advancements in medicine. The Structural Biology is widely used in the Pharmaceutical Industries to understand the biological processes and laying the foundation for the advancements in the field of drug designing, its effect on the disease diagnosis further steps of treatment and prevention. This thus results in an expansion of the pharmaceutical industries encouraging the growth of life for Animal & Human Health Care.
Structural Biology are interrelated disciplines allowing computational methods to analyse biological data and develop algorithms and Analytical methods by acquiring knowledge from various disciplines like computer science, physics, statistics etc. This field is gaining importance in various research fields like Neural Networks, Artificial Intelligence for developing algorithms.
Seoul is the capital and biggest city in South Korea. The official name of the city is the Seoul Special Metropolitan City which is in the northwest piece of South Korea on the Han River. As of January 2017, the number of inhabitants in Seoul is 10,197,604 individuals. The rambling metropolitan zone is a lot bigger at 25.6 million people groups subsequently it is the fifth most crowded on the planet. Seoul is noted for its populace thickness, which is twice that of New York and multiple times more prominent than Rome. Seoul involves 605 square kilometers (234 square miles), with a sweep of around 15 kilometres (9 miles), generally cut up into northern and southern parts by the Han River. The city is circumscribed by eight mountains, and additionally the more dimension terrains of the Han River plain and western zones.
Structural science is the most established of every biological branches and it is still developing field. The principal objective of basic science is to accomplish a total comprehension about the cell structure in connection to the sub-atomic instruments engaged with the cell forms. New bits of knowledge are as of now developing into the macromolecular structures which includes in the signal transduction. It incorporates a full scope of relationship from tissues to atoms. Basic science has an extremely wide range and is much expanded.
- Alteration In The Protein Structure
- Structural Modification In Nucleic Acids
- Dimensions In Structure Determination
Biochemistry is the branch of science in which deals with the study the chemical and physical processes that occurs in an organism. It integrates an introduction to the structure of macromolecules and a biochemical approach to cellular function. It includes the study of things as the structures and physical properties of biological molecules, including proteins, carbohydrates, lipids, and nucleic acids; the mechanisms of enzyme action; the chemical regulation of metabolism; the chemistry of nutrition; the molecular basis of genetics; the chemistry of vitamins; energy utilization in the cell; and the chemistry of the immune response.
Biophysics involves the study of biological systems and biological processes using physics-based methods or based on physical principles. It is an interdisciplinary research area between physics and biology. Biological phenomena and Living nature can be explored using the principles and methods applied in physics.
- Cellular And Molecular Biology
- Plant Biochemistry
Cell and Molecular Biology is an interdisciplinary field of science that deals with the fields of chemistry, structure and biology as it seeks to understand life and cellular processes at the molecular level. Molecular cell Biology mainly focuses on the determination of cell fate and differentiation, growth regulation of cell, Cell adhesion and movement, Intracellular trafficking. The relationship of signalling to cellular growth and death.
- Cell Biology
- Biological Hypothesis
- Fragmentation Of DNA
Genetherapy basically involves the introduction or alteration of genetic material within a cell or organism with an intention of curing the disease. Both cell therapy and gene therapy are overlapping fields of biomedical research with the goals of repairing the direct cause of Genetic diseases in DNA or cellular population respectively, the discovery of recombinant DNA technology in the 1970s provided tools to efficiently develop gene therapy. Cell Therapy or Cyto therapy is the transfer of cells into a patient with a goal of improving the disease. From beginning blood transfusions were considered to be the first type of cell therapy to be practised as routine. Later, Bone marrow transplantation has also become a well-established concept which involves treatment of much kind of blood disorders including anaemia, leukaemia, lymphoma and rare immunodeficiency diseases.
- Vectors Used In Gene Therapy
- Viral Gene Therapy
- Gene Therapy For Diseases
Molecular Biology is the field of biology that studies the composition, structure, and interactions of cellular molecules likenucleic acids and proteins which carry out the biological processes essential for the cell's functions and maintenance. Itcovers a wide scope of problems that are related to molecular and cell biology including structural and functional genomics,transcriptomics, proteomics,bioinformatics, biomedicine, molecular enzymology, molecular virology &molecular immunology etc.
Microbiology involves the study of the micro-organisms that are too small to be seen by naked eyes. It includes eukaryotes such as fungi and protists and prokaryotes such as bacteria and certain algae.
- Interactions of cellular molecules
- Molecular virology
Protein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence—that is, the prediction of its folding and its secondary and tertiary structure from its primary structure. Structure prediction is fundamentally different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry.
- Inverse problem of protein design
- Bioinformatics and theoretical chemistry
- Amino acid sequence
Chemistry of amino acids and protein structure. Concerning this, one should know the structure of a biomolecule which is very important if we want to know the living systems and diseases. A database is a structured combination of data. In the field of structural biology immense research is being done and as the result, huge data is being produced. To store the data in an organized manner, bioinformatics databases are used. Many databases are designed so that the biological data can be stored such as sequence databases, signaling database, structure database, etc. The Protein database(PDB) which is a crystallographic database is used for 3D structural data of larger biomolecules. The advancement in technologies had been considered in the further development of the PDB and in the structural specialty and structural characteristic databases that have also evolved. The mainly used databases are Electron Microscopy Data Bank, Protein Structure Classification Database (CATH), Structural Classification of Protein (SCOP) and Protein Data Bank (PDB).
- Protein Data Bank
- Electron Microscopy Data Bank
- Protein Structure Classification Database
Structural Bioinformatics is a Structural Biology which characterizes Biomolecules and their arrangement at the Molecular and atomic level. Structural Bioinformatics is related to the prediction and analysis of the three dimensional structure of macromolecules such as Protein, DNA, RNA. It deals with the generalization of overall folds, interactions, local motifs, structure and functional relationship and molecular folding of experimentally solved structures and Computationally predicted structure.
- The prediction and analysis of 3D structure
- Computationally predicted structure
- Molecular folding
Planning of medication surely alluded as level headed medication outline or essentially discerning plan, it is the innovative procedure of finding or planning new prescriptions in view of the information of an organic targets. This medication is regularly a natural little particle that enacts or restrains the capacity of a macromolecule, for example, a protein, which thus drives a restorative advantage to the patient. Medication plan most regularly yet not really relies upon PC demonstrating strategies. This sort of displaying is now and then called as PC supported medication plan. At long last, sedate plan that relies upon the learning of the three-dimensional structure of the bio atomic target is known as structure-based medication outline. Notwithstanding little atoms, biopharmaceuticals and particularly restorative antibodies are an undeniably essential class of medications and computational techniques for enhancing the liking, selectivity, and soundness of these protein-based therapeutics have additionally been produced.
- Drug Targets
- Structure based drug design
- Ligand based drug design
Enzymology involves the study of enzymes, their kinetics, structure, and function, as well as their relation to each other. Enzymes play an important role in all metabolic and cellular signaling pathways. Scientists are often interested in understanding how enzymes function at the molecular and atomic level through a combination of modern biochemistry and structural biology. Techniques used to investigate enzyme structure and dynamics include X-ray crystallography, NMR, mass spectroscopy and protein chemistry, while their chemical behavior is being characterized by rapid-reaction and steady-state kinetics, calorimetry, chemical analyses, and a variety of spectroscopies. Protein engineering is also used to study how structure determines function.
- Protein Engineering
- Protein prenylation Techniques
- Steady state kinetics
Computational approaches are benefits for structural biology. Structure of molecules is determined by experimental methods which are tedious and practical. Computational biology is an interdisciplinary field that develops and applies computational methods to analyze large collections of biological data, such as genetic sequences, cell populations or protein samples, to make new predictions or discover new biology. The computational methods used include analytical methods, mathematical modeling, and simulation. It is a rapidly developing multi-disciplinary field. The systematic achievements of data made possible by genomics & proteomics technologies have created a tremendous gap between available data & their biological interpretation.
- Homology modeling
- Ab-initio method
Basic virology is the scrutiny of viruses, ultramicroscopic, parasitic particles of hereditary material contained in a protein coat infection like operators. It depicts the fundamental sub-atomic instruments corresponding with infections to invade target cells, initiates a contamination and corroborate that offspring infection particles are unveiled into nature. Virology accentuation basic reason for understanding the atomic components of layer combination utilized by envelope infections to penetrate an objective cell, their approaches to taint and endeavour cells for propagation, their cooperation with creature physiology and invulnerability, the sicknesses they cause, the methods to segregate and culture them, and their utilization in research and treatment. Virology is thought to be a sub-discipline of microbiology or pathology.
- Protein coat infection
- Virus Replication
Practically about 600 bioinformatics tools were advanced over the past two years and are being used to facilitate data analysis and its interpretation.Web assistance in bioinformatics provides interfaces that have been developed for an ample array of applications for bioinformatics. The main enhancement derived from the fact that end users do not have to deal with software and database preservation overheads.There are differing software predominant for bioinformatics like open source, sequence,alignment, healthcare, freeware moleculargraphic systems and moleculatr mechanic models.
Structural bioinformatics is a branch of bioinformatics that deals with the three-dimensional structure of biological macromolecules such as proteins,RNA and DNA.Structural bioinformatics deals with generalizations about macromolecular 3D structure such as comparisons of overall folds and local motifs, principles of molecular folding, evolution, and binding interactions, and structure/function relationships. Evolutionary Bioinformatics is an advanced field that addresses the practice of data processing and the engineering of data for the investigation of biological evolution.
- Binding interactions
- Investigation of biological evolution.
- Macromolecular 3D structure determination
Molecular modelling exhibits all the hypothetical methods and computational procedures used to mimic the behavior of macromolecules. In conventional monoscale modeling and simulation approaches, the scope and validity of a biological model is restricted to a specific time and space scale.
Molecular simulation requires the use of the efficient computers in stimulating the interactions among the atoms to study the material properties, these simulations based on the methods help in the quantum mechanical results ranging from atoms to clusters of molecules based on the time from milliseconds or longer. Molecular Graphics helps in characterizing the global and local properties of molecules, processes and chemical
- Drug Design
- Enzyme Catalysis
- Molecular Recognition Of Proteins, DNA
Genome informatics is the field in which computer and measurable procedures are connected to get biological data from genome sequences. A genome is accomplished arrangement of DNA of living organisms, including of every one of its qualities. Genome informatics incorporates strategies to analyse DNA sequence data and to anticipate protein grouping and structure and it goes for the aggregate portrayal and capability of qualities which coordinate the generation of proteins with the help of catalysts and delivery person particles.
- Analyse DNA sequence data
- Generation of proteins
- Genome sequences
With the increase in studies of biosciences and urge of emerging computational and experimental techniques, the application of the computational tools and expertise in the biophysics has led the way for emerging computer programming for the immense biological studies. Computer programs predict atomic, molecular properties and reaction paths for chemical reactions of biomolecules. Structural genomics emphasizes high throughput of every protein encoded by the genome determining protein structures. These methods help in scrutinizing the protein structures which are cost effective and time conservative.
- Biological Sequence Analysis
- Electronic Structure Theory
- Computational Approaches
Computational genomics refers to the use of computational and statistical analysis to decipher biology from genome sequences ,including both DNA and RNA sequence as well as other "post-genomic" data (i.e., experimental data obtained with technologies that require the genome sequence, such as genomic DNA microarrays). These, in combination with computational and statistical approaches to understanding the function of the genes and statistical association analysis, this field is also often referred to as Computational and Statistical Genetics/genomics. As such, computational genomics may be regarded as a subset of bioinformatics and computational biology.
- Human Genome Project
- Contribution Of Computation Genomics Research To Biology
- Cancer Genomics
Proteomics includes studies of composition, structure, function, and interaction of the proteins directing the activities of each living cell. It is the branch of molecular biology concerned with the study of proteome.
Genomics is the sub-discipline of genetics devoted to mapping, sequencing and functional analysis of genomics. It studies all the genes present in an organism. It includes the study of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genomes.
- Analysis Of Gene Expression
- Targeting Signal Networks
- Enzyme Linked Protein Receptors
Computational neuroscience is a branch of neuroscience which employs mathematical models, theoretical analysis and abstractions of the brain to understand the principles that govern the development, structure and cognitive abilities of the nervous system. Computational neuroscience focuses on the description of biologically plausible neurons and their physiology and dynamics, and it is therefore not concerned with biologically unrealistic disciplines such as connectionism, machine learning, neural networks, artificial intelligence and computational learning theory.
- Artificial intelligence
- Computational learning theory.
- Neural networks
Molecular Genetics is the field of science that reviews the structure and capacity of qualities at a molecular level and along these lines utilizes strategies for both molecular biology and genetics. The study of chromosomes and gene expression of an organism can give knowledge into heredity, geneticvariation and transformations.The examination of Genetics at the level of the basic building squares of cells and at the DNA level. Cells are as mind boggling as they are little and much is as yet obscure about the internal workings of these building pieces of life. In the event that you'd get a kick out of the opportunity to log hours in a lab and use utilize propelled equipments to help propel the comprehension of how cells function, thinks about in cell and nuclear science.
- The study of chromosomes
- Gene expression
- Genetic variation and transformations
Structural & Computational Biology USA Universities
Past Conference Report
Computational and Structural Biology 2018 Report
We gratefully thank all our wonderful Speakers, Conference Attendees, Students, Media Partners, Associations and Exhibitors for making Computational and Structural Biology 2018 Conference the successful!
EuroSciCon Conference on Computational and Structural Biology 2018, hosted by the Euroscicon Ltd. was held during Dec 6-7,2018 at Hotel Hyatt place, Amsterdam, Netherlands based on the theme “Futuristic Technologies and Novel Implementation in Computational and Structural Biology”
which got magnificent response. With the support and guidance of Organizing Committee Members and Editorial Board Members and astonish presentations of all participants along with Scientists, Researchers, Students and leaders from various fields of Computational Biology made this event a grand success.
Euroscicon Ltd expresses its gratitude to the conference Moderator, namely Dr.Abhishek Basu, University of Kalyani, West Bengal for taking up the responsibility to coordinate during the sessions for smooth functioning of this event. We are indebted to your support. A very special thanks to our Exhibitors and Sponsors to have bestowed and their faith and invested in us to make this event a fruitful one. We hope you continue your support in our future endeavours.
The meeting reflected various sessions, in which discussions were held on the following major scientific tracks:
- Structural Biology
- 3D Structure Determination
- Computational Methods and Biology
- Drug Designing
- Development Of Biomarkers
- Signalling Biology
- Hybrid Approaches for drug prediction
- Cellular and Molecular Biology
- Deep Sequencing
- Frontiers in Structural Biology
- Structural Biology in Cancer research
- Biochemistry and Biophysics
- NMR and Mass spectroscopy
- Structural Enzymology
- Computational Genomics
- Biomedical Engineering
- Computational Biology
Euroscicon Ltd also took the privilege of felicitating Computational and Structural Biology 2018 Organizing Committee, Editorial Board Members of Biochemistry and Molecular Biology, Keynote Speakers, Chair and Co-Chairs, Moderator and Exhibitor who supported this event. With the grand success of Computational and Structural Biology 2018, Euroscicon Ltd is proud to announce the Computational and Structural Biology 2019 is going to be held soon
For More details visit: https://computational-structuralbiology.euroscicon.com/